Gene information
Official symbol CHRNA5
Official full name cholinergic receptor nicotinic alpha 5 subunit
Gene type protein-coding gene
Chromosome15q25.1
Gene familyCholinergic receptors nicotinic subunits
Resources
Entrez Gene 1138
HGNC HGNC:1959
Ensembl ENSG00000169684
Vega OTTHUMG00000143858
UCSC uc002bdy.3
GO terms: 28 records
GO Description Category LogP Number of genes Detail
GO:0001505 regulation of neurotransmitter levels GO Biological Processes -3.63969141 10 More
GO:0005261 cation channel activity GO Molecular Functions -1.68739377 23 More
GO:0007268 chemical synaptic transmission GO Biological Processes -4.44678751 35 More
GO:0007610 behavior GO Biological Processes -18.1916656 76 More
GO:0017157 regulation of exocytosis GO Biological Processes -7.48561663 15 More
GO:0030594 neurotransmitter receptor activity GO Molecular Functions -2.67300750 6 More
GO:0035094 response to nicotine GO Biological Processes -8.07167727 14 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0043235 receptor complex GO Cellular Components -19.4198369 40 More
GO:0045211 postsynaptic membrane GO Cellular Components -5.83105498 30 More
GO:0046928 regulation of neurotransmitter secretion GO Biological Processes -1.71479923 4 More
GO:0050804 modulation of chemical synaptic transmission GO Biological Processes -15.2260557 60 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051588 regulation of neurotransmitter transport GO Biological Processes -2.92721908 6 More
GO:0060078 regulation of postsynaptic membrane potential GO Biological Processes -2.74505261 11 More
GO:0060627 regulation of vesicle-mediated transport GO Biological Processes -25.1756709 46 More
GO:0098794 postsynapse GO Cellular Components -5.82876983 23 More
GO:0098797 plasma membrane protein complex GO Cellular Components -14.6387951 39 More
GO:0098802 plasma membrane signaling receptor complex GO Cellular Components -6.47096721 17 More
GO:0098916 anterograde trans-synaptic signaling GO Biological Processes -4.44678751 35 More
GO:0098960 postsynaptic neurotransmitter receptor activity GO Molecular Functions -2.86473787 9 More
GO:0099177 regulation of trans-synaptic signaling GO Biological Processes -15.1793607 60 More
GO:0099536 synaptic signaling GO Biological Processes -6.00976162 42 More
GO:0099537 trans-synaptic signaling GO Biological Processes -5.17038357 38 More
GO:1903305 regulation of regulated secretory pathway GO Biological Processes -6.01402466 11 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling GO Biological Processes -7.80587066 38 More
GO:2000300 regulation of synaptic vesicle exocytosis GO Biological Processes -2.35732458 4 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
Drug-Gene interaction
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Related drugs: 4 records
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
NM_000745.3:c.[107-1865T>C;1192G>A] genomics death[prognosis (bad)] acute myocardial infarction Coverstone ED et al. Basic Res Cardiol. 2018
NM_000745.3:c.1192G>A genomics smoking cessation[other] acute myocardial infarction Chen LS et al. Nicotine Tob Res. 2014
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